Back when I followed roadracing a "cassette" gear box was the name given to transmission gears that could be removed from the engine via an access panel on the side of the engine, while keeping everything else in the motor/trans intact. In racing its common to change gearing for each track, so that was why it was used in that application. The ST1100 doesn't use that style gear box, or at least I've never heard it ever mentioned here before.Upt 'North, That's what we have on our ST1100's cassette gear boxes. Been a long long time since I have seen a transmission problem on a cassette box on a Honda. I think Yamaha's FJR 1300 uses them too. So ain't nothing wrong with the design. Me thinks its BMW's supplier of parts that has a Quality issue.
Not sure if that's the same cassette gear box used in the BMW 1600 or not, I'm not familiar with that bike.